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Preventing cancer through life style choices

In 2001 the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) WCRF/AICR set themselves the task of systematically assessing all good research on diet, physical activity and cancer and publishing a report that would be the largest study of its kind with conclusions that would be best the evidence could demonstrate.  Over 100 scientists from 30 countries were involved.  An expert panel of 21 of these scientists worked for 5 years to produce the report "Food, Nutrition, Physical Activity, and the Prevention of Cancer: a Global Perspective."  The follow-up companion Policy Report "Policy and Action for Cancer Prevention"  was published a little over a month ago and has recommendations for a series of different groups and organizations including government, industry, the media, schools, and work places

Recent research: prevention & treatment of overweight with changed eating behaviours, energy density & breastfeeding

Here are six studies on eating and weight.  The first, by Maruyama and colleagues, demonstrates a strong association between both "eating until full" and "eating quickly" and the chances of being overweight.  The linked BMJ editorial by Denney-Wilson & Campbell discusses these findings further, including suggesting that "Clinicians should encourage parents to adopt a child led feeding strategy that acknowledges a child's desire to stop eating that begins from birth. Reassure parents that well children don't starve."  Unfortunately Llewellyn et al show that eating rate seems to be partly genetically determined - an even stronger reason to work hard to go against any tendency to gobble food.  The Denney-Wilson editorial gives other ways to encourage weight loss, and Leahy and colleagues underlines the value of one such approach - reducing the energy density (ED) of diets " ...  by decreasing fat and sugar and by increasing fruit and vegetables."  Children whose diet was changed in this way " ...

Recent research: fish and n-3 fatty acids

Fish, fish oils, and n-3 fatty acids are often in the health news.  Here are seven recent papers illustrating the breadth of fish oil relevance.  The papers look at treatment of rheumatoid arthritis, the potential of flax as a dietary source of n-3 fatty acids, effects on indicators of cardiovascular disease, potential protection against dementia, reduction in mortality, and importance in pregnancy.  The papers also illustrate the patchwork, three steps forward/one step back, meandering, spreading, accretion of scientific knowledge.  As the proverb goes "One swallow doesn't make a summer".  Similarly, a single research study is usually simply one brick in the gradual building of our knowledge.  For more on fish and n-3 fatty acids, see other relevant blog posts I've written, articles in the linked Connotea database, and some recommended websites.     

Recent research: mothers, children & depression

Here are five recent papers on mothers, families, children and depression.  The first is a freely viewable editorial by Markowitz which begins with a quote from the Aeneid "I cannot bear a mother's tears".  Markowitz looks at evidence demonstrating the importance of both nature (genetic risk) and nurture (effects of the mother-child relationship and other environmental factors) on psychological outcomes.  The second paper is a good overview of postnatal depression by Musters et al.  Unfortunately the full text is only viewable if you are a BMJ subscriber or if you pay for the article (or contact the authors).  The third study looks at the benefits for children of effective treatment for maternal depression.  The fourth paper - a freely viewable editorial by Reiss - looks both at the effects of maternal depression on children and the effects of children's psychological symptoms on mothers.  The fifth study is unusual and interesting as it compares the effects of parental depression on both nonadopted and on adopted children.

Markowitz, J. C. (2008). "Depressed Mothers, Depressed Children." Am J Psychiatry 165(9): 1086-1088. [Free Full Text]

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