Here are two papers on mindfulness and four on sleep.  The Kuyken et al paper is important.  It compares mindfulness-based cognitive therapy (MBCT) with continuation antidepressants in the prevention of relapse in recurrent depression.  The results are great - "Relapse/recurrence rates over 15-month follow-ups in MBCT were 47%, compared with 60% in the m-ADM (maintenance antidepressant) group (hazard ratio = 0.63; 95% confidence interval: 0.39 to 1.04).  MBCT was more effective than m-ADM in reducing residual depressive symptoms and psychiatric comorbidity and in improving quality of life in the physical and psychological domains."  I have been cautious in my enthusiasm for MBCT (see previous post) but this is exactly the kind of research that we need to help clarify MBCT's potential further.  The second paper on mindfulness is lower key.  It is a mention of its potential in enhancing sexuality.  It makes sense - see last month's posts on the effects of meditation training on experiencing positive emotions - but the relevant research is still in its early stages. 

Here's a gutsy, nutritional, low sunlight kind of blog post to suit our post-holiday season.  First the gutsy bit.  Irritable bowel syndrome (IBS) - with its characteristic symptoms of abdominal pain, altered bowel habit, and possibly bloating - is very common, affecting about 15% of the population.  Ford et al systematically reviewed all research on treating IBS with fibre, antispasmodics, or peppermint oil.  Fibre was some use, but only in the form of ispaghula (UK Fybogel, Isogel).  The antispasmodics otilonium and hysocine (UK Buscopan) seemed also to be of help.  But what attracted me to the study was the finding that most helpful of the three treatments seemed to be the old-fashioned remedy of taking peppermint oil. 

Here are six studies on eating and weight.  The first, by Maruyama and colleagues, demonstrates a strong association between both "eating until full" and "eating quickly" and the chances of being overweight.  The linked BMJ editorial by Denney-Wilson & Campbell discusses these findings further, including suggesting that "Clinicians should encourage parents to adopt a child led feeding strategy that acknowledges a child's desire to stop eating that begins from birth. Reassure parents that well children don't starve."  Unfortunately Llewellyn et al show that eating rate seems to be partly genetically determined - an even stronger reason to work hard to go against any tendency to gobble food.  The Denney-Wilson editorial gives other ways to encourage weight loss, and Leahy and colleagues underlines the value of one such approach - reducing the energy density (ED) of diets " ...  by decreasing fat and sugar and by increasing fruit and vegetables."  Children whose diet was changed in this way " ...

Here are five studies on the loose theme of how the mind affects the body, and the body affects the mind ... and that the distinction between mind and body is pretty arbitrary anyway.  Using meta-analysis, Chida & colleagues highlight considerable evidence suggesting that stress-related psychosocial factors have an adverse effect on cancer incidence and survival.  Andersen & colleagues report a randomized controlled trial to respond to this in women diagnosed with breast cancer.  Women in the stress management arm of the study received an initial one-year, 26 session intervention in groups of 8 to 12 people.  The aim was to reduce distress and improve quality of life, improve health behaviors (diet, exercise, smoking cessation), and facilitate cancer treatment compliance and medical follow-up.

Five of these six studies are from last month's American Journal of Psychiatry.  Kendler et al discuss the many similarities and only occasional differences between bereavement-related and other life event-related depression - an issue explored further in Maj's editorial.  Li et al show that depression in pregnancy (exacerbated further by stressful life events and obesity) increases the risk of preterm delivery.  Miklowitz reviews research on the value of adjunctive psychotherapy for bipolar disorder sufferers (already taking medication) and discusses the various ways it can be helpful.  Oquendo et al (in a freely viewable editorial) argue that suicidal behaviour should be placed on a "separate axis" in the next version of the DSM diagnostic system.  Finally Vertanen et al, in an interesting study, demonstrate that increased hospital overcrowding - measured by bed occupancy rates - is associated with increased use of antidepressants by hospital staff.

Kendler, K. S., J. Myers, et al. (2008). "Does Bereavement-Related Major Depression Differ From Major Depression Associated With Other Stressful Life Events?" Am J Psychiatry 165(11): 1449-1455.  [Abstract/Full Text]  

Here are half a dozen recent studies on men & women.  Elliot & Niesta found that red, relative to other colours, lead men to view women as "more attractive and sexually desirable".  Holt-Lundstad & colleagues randomized couples to a "support enhancement intervention" involving shared gentle massage for 30 minutes three times weekly or a control group.  There were encouraging effects of the "warm touch" on multiple stress-sensitive systems including husbands' blood pressure.  Koo et al found that writing about how something good might not have happened (e.g. how one might never have met one's romantic partner) produced more satisfaction (with the relationship) than writing about how the positive event actually had happened (e.g.

Here are a couple of studies on smoking, a couple on B vitamins, a couple on vitamin D, and an intriguing study on iron.  The smoking papers underline the varieties of damage this habit produces.  So the Pasco et al study shows that, for women, being a smoker is associated with double the risk of developing subsequent major depression.  The Strandberg research challenges any notion of "Eat, drink and be merry for tomorrow we die".  This study of 1658 men reports that "During the 26-year follow-up of this socioeconomically homogeneous male cohort, HRQoL (quality of life) deteriorated with an increase in daily cigarettes smoked in a dose-dependent manner.

Here are half a dozen recent studies involving cognitive therapy (CBT).  The first by Craigie et al explores the use of mindfulness-based cognitive therapy (MBCT) to treat generalized anxiety disorder (GAD).  Although, as one would expect, MBCT helped GAD sufferers, it was noteworthy that results "fall well short of outcomes achieved by past research".  This adds to my concern that mindfulness training may at times be being over-hyped - see a blog I wrote in September for for more on this.  The next study by Cuijpers et al also suggests limitations to the march of CBT with interpersonal psychotherapy looking a somewhat better candidate for prevention of depression onset.  I guess one could argue that CBT can - and probably more often should - include  behavioural interventions to promote improved relationships.  Click here for tools that can help this approach.   The third piece of research by Grey et al is exciting.  It challenges the Alice in Wonderland dodo bird suggestion that "everyone has won, and all must have prizes"

In the end the love you take is equal to the love you make.   Beatles

This is essentially the Beatles closing statement. It is the last lyric on the last album they recorded.
(Let It Be was the last album they released, but it was recorded earlier).

Fish, fish oils, and n-3 fatty acids are often in the health news.  Here are seven recent papers illustrating the breadth of fish oil relevance.  The papers look at treatment of rheumatoid arthritis, the potential of flax as a dietary source of n-3 fatty acids, effects on indicators of cardiovascular disease, potential protection against dementia, reduction in mortality, and importance in pregnancy.  The papers also illustrate the patchwork, three steps forward/one step back, meandering, spreading, accretion of scientific knowledge.  As the proverb goes "One swallow doesn't make a summer".  Similarly, a single research study is usually simply one brick in the gradual building of our knowledge.  For more on fish and n-3 fatty acids, see other relevant blog posts I've written, articles in the linked Connotea database, and some recommended websites.